Mueller-Anneling, L, Avol E, Peters JM, Thorne PS. 2004.
Ambient Endotoxin Concentrations of PM10 from Southern California
Environmental Health Perspectives (EHP), Vol. 112 No. 5, pp. 583-588.
This study reported outdoor air concentrations of particles (PM10) and the associated endotoxin component, which were measured at defined intervals during one year in 13 Southern CA communities (re: USC Children's Health Study). PM10 and endotoxin concentrations in outdoor air, by volume, were higher in communities downwind of Los Angeles.
Exposure to PM10 has been associated with airway inflammation and asthma episodes and related symptoms in children and adults like wheezing. (NOTE: Please see CAFA Briefing Kit, "Asthma and Outdoor Air Quality") Endotoxin is a lipopolysaccharide componennt of the cell wall of gram-negative bacteria, which when inhaled may start airway inflammation; endotoxin concentrations measured inside homes during previous studies were associated with adverse respiratory health outcomes. |
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